Mitaban Dip - Pfizer is a liquid concentrated of amitraz and is indicated for topical treatment of generalized demodicosis (Demodex canis) in dogs. Mitaban is applied as a dip after a cleansing shampoo.
CONTRAINDICATIONS
Fertility impairment studies have not been conducted in the canine with MITABAN (amitraz). It is not known whether MITABAN may cause impairment of fertility in dogs. Reproduction studies during pregnancy have not been conducted with MITABAN. It is not known whether MITABAN may harm the embryo or fetus. The safey of MITABAN has not been established for dogs less than four months of age. The safety of MITABAN has not been established for dogs less than four months of age.
Dosage and Administration:
Long and medium-haired dogs should be clipped closely before treating. Prior to the initial treatment, all dogs should be bathed with a mild soap and water and towel dried. The entire animal should then be topically treated with MITABAN (amitraz) at a rate of 10.6 milliliters (contents of one bottle) per 2 gallons of warm water (250 ppm active drug). Two bottles (21.2 milliliters) per four gallons of water may be necessary to treat large dogs. The entire dog should be thoroughly and completely wetted with the mixture, and then allowed to air dry. Do not rinse or towel dry the dog after treatment with MITABAN. A fresh MITABAN-water mixture should be prepared for each patient; using the same mixture for more than one patient can spread other dermal infections and also the concentration of MITABAN could be reduced to a level which would be less effective than the recommended concentration.
Three to six topical treatments (14 days apart) are recommended for treatment of generalized demodicosis. It is important to continue the treatment until no viable (alive) mites are found in the skin scrapings at two successive treatments, or until six treatments have been applied. Severe (chronic) cases and dogs which are reinfested may require a second and third series of treatments, and again the treatment should be applied at 14 day intervals. Discontinue treatment of dogs which do not respond clinically.
When employing MITABAN for treatment of demodicosis, other dogs in the home also should be examined for lesions to ascertain whether treatment of these animals is warranted.
Adverse Reactions and Side Effects:
The most frequently observed adverse reaction is transient sedation, which occurs in approximately 8% of the generalized demodicosis patients. This effect occurs within 2 to 6 hours posttreatment, and usually dissipated within 24 to 72 hours. Sedation is often less apparent when additional MITABAN (amitraz) treatments are applied, however in approximately 35% of the generalized demodicosis patients sleepiness is observed after each treatment. Transient pruritus, which clinical investigators considers to be an indirect effect due to an inflammatory reaction associated with dead mites, occurs in less than 3% of the generalized demodicosis patients.
Animals treated with MITABAN (amitraz) should not be subjected to additional stress for a period of at least 24 hours posttreatment.
How Supplied:
MITABAN Liquid Concentrate (amitraz) is available in cartons of 12-10.6 mL bottles.
Store at controlled room temperature 20° to 25°C (68° to 77°F).
Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian.
Additional information not available for this medicine.