VANGUARD PLUS 5 L4 Modified Live Virus Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterin For use in dogs only Vanguard Plus 5 L4 is for vaccination of healthy dogs 6 weeks of age or older as an aid in preventing canine distemper caused by canine distemper (CD) virus, infectious canine hepatitis (ICH) caused by canine adenovirus type 1 (CAV-1), respiratory disease caused by canine adenovirus type 2 (CAV-2), canine parainfluenza caused by canine parainfluenza (CPI) virus, enteritis caused by canine parvovirus (CPV), and leptospirosis caused by Leptospira canicola, L. grippotyphosa, L. icterohaemorrhagiae, and L. pomona. DIRECTIONS: General Directions: Vaccination of healthy dogs 6 weeks of ager or older is recommended. Aseptically rehydrate the freeze-dried vaccine (Vanguard Plus 5 L4) with the sterile gel provided, shake well, and administer 1 mL subcutaneously or intramuscularly. Primary Vaccination: Healthy dogs should receive 2 doses administered 3 weeks apart. To avoid the potential for maternal antibody interference, dogs vaccinated at less than 9 weeks of age should receive 3 doses, each administered 3 weeks apart. Revaccination: Annual revaccination with a single dose is recommended, although, as recommended by the American Veterinary Medical Association and its Council on Biologic and Therapeutic Agents, the attending veterinarian should determine the frequency of revaccination based on the animal’s lifestyle and risk of exposure. PRECAUTIONS: Store at 2°-7°C. Prolonged exposure to higher temperatures and/or direct sunlight may adversely affect potency. Do not freeze. Use entire contents when first opened. Sterilized syringes and needles should be used to administer this vaccine. Do not sterilize with chemicals because traces of disinfectant may inactivate the vaccine. Burn containers and all unused contents. Contains gentamicin as preservative. Vaccination of pregnant bitches should be avoided. In case of anaphylaxis, administer epinephrine or equivalent.
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