Amoxicillin

Biomox Tablets (amoxicillin) is a broad-spectrum, semi-synthetic antibiotic which provides bactericidal activity against a wide range of common gram-positive and gram-negative pathogens. Amoxicillin chemically is D-(-)a-amino-p-hydroxybenzyl penicillin trihydrate.

BIOMOX tablets are indicated in the treatment of the following infections in dogs when caused by susceptible strains of organisms:

• Bacterial Dermatitis due to Staphylococcus aureus, Streptococcus, Staphylococcus and E. coli.
• Soft Tissue Infections (abscesses, wounds, lacerations) due to Staphylococcus aureus, Streptococcus , E. coli, Proteus mirabilis and Staphylococcus.

Amoxicillin has bactericidal activity against susceptible organisms similar to that of ampicillin. It acts by inhibiting the biosynthesis of bacterial cell wall mucopeptides. Most strains of the following gram-positive and gram-negative bacteria have demonstrated susceptibility to amoxicillin, both in vitro and in vivo nonpenicillinase-producing staphylococci, alpha- and beta-hemolytic streptococci, Streptococcus faecalis, Escherichia coli and Proteus mirabilis. Amoxicillin does not resist destruction by penicillinase; therefore, it is not effective against penicillinase-producing bacteria, particularly resistant staphylococci. Most strains of Enterobacter and Klebsiella and all strains of Pseudomonas are resistant.

Amoxicillin may be given without regard to meals because it is stable in gastric acid. It is rapidly absorbed following oral administration and diffuses readily into most body fluids and tissues. It diffuses poorly into the brain and spinal fluid except when the meninges are inflamed. Most of amoxicillin is excreted in the urine unchanged.

Dosage and Administration:

The recommended dosage is 5 mg per pound of body weight administered twice daily for 5 to 7 days or 48 hours after all symptoms have subsided. If no improvement is noted in 5 days, the diagnosis should be reconsidered and therapy changed.

Contraindications: The use of amoxicillin is contraindicated in animals with a history of an allergic reaction to penicillin.

Adverse Reactions:

Amoxicillin is a semisynthetic penicillin and, therefore, has the potential for producing allergic reactions. Epinephrine and/or steroids should be administered if an allergic reaction occurs.

For use in dogs only

Precautions:
Until adequate reproductive studies are accomplished, Biomox (amoxicillin) tablets should not be used in pregnant or breeding animals.

Federal law restricts this drug to use by or on the order of a licensed veterinarian

Inactive Ingredients: Dibasic Calcium Phosphate Dihydrate, Magnesium Stearate, Microcrystalline Cellulose and Sodium Starch Glycolate.

How Supplied:
Biomox (amoxicillin) tablets are supplied in 50 mg, 100 mg and 200 mg concentrations in bottles of 500 and 1000 tablets.

Store at controlled room temperature between 15° and 30°C (59°F and 86°F)

Virbac Animal Health